The ratio of physiologic dead space to tidal volume is usually about 1/3. Alveolar dead space is the volume of gas within unperfused alveoli (and thus not participating in gas exchange either) it is usually negligible in the healthy, awake patient. Anatomic dead space is the volume of gas within the conducting zone (as opposed to the transitional and respiratory zones) and includes the trachea, bronchus, bronchioles, and terminal bronchioles it is approximately 2 mL/kg in the upright position. The volume of gas in the airways only (ie, gas proximal to the respiratory bronchiole including mouth, nose, and ventilator tubing) represents anatomic dead space (no gas exchange is possible). Therefore, physiological VD anatomic VD + alveolar VD. The Bohr equation, named after Danish physician Christian Bohr (18551911), describes the amount of physiological dead space in a persons lungs. Physiologic dead space The figure depicts dead space. Physiologic or total dead space is the sum of anatomic dead space and alveolar dead space. The sum of the two types of dead space is physiological dead space volume. a space remaining in the tissues as a result of failure of proper closure of surgical or other wounds, permitting the accumulation of blood or serum. Dead space is the volume of a breath that does not participate in gas exchange. When alveolar capillaries are obstructed (e.g., PE), inhaled air entering this region of the lung cannot participate in gas exchange, and therefore functions no.
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